Catégorie
Irinotecan
Numéro CAS
Irinotecan Hydrochloride Trihydrate STD - 136572-09-3 : IMP - C - 947687-02-7 : IMP - E - 86639-52-3 : IMP - L - 1255644-71-3 : IMP - M - 185336-12-3
Autre numéro CAS
Free Base - 97682-44-5 , HCL - 100286-90-6
Formule moléculaire
Irinotecan Hydrochloride Trihydrate STD - C33H45ClN4O9 : IMP - C -C35H42N4O6 : IMP - E - C22H20N2O5 : IMP - L - C33H38N4O6 : IMP - M - C33H38N4O7;
Masse moléculaire
Irinotecan Hydrochloride Trihydrate STD - 677.18 g/mol : IMP - C - 614.73 g/mol : IMP - E - 392.4 g/mol : IMP - L - 586.68 g/mol : IMP - M - 602.68 g/mol;
Synonyme

Irinotecan Hydrochloride Trihydrate - (S)-4,11-Diethyl-4-hydroxy-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3`,4`:6,7]indolizino[1,2-b]quinolin-9-yl [1,4`-bipiperidine]-1`-carboxylate hydrochloride trihydrate ; (4S)-4,11-Diethyl-4-hydroxy-3,14-dioxo-3,4,12,14-;

Irinotecan EP  Impurity - C  -  (4S)-4,8,11-triethyl-4-hydroxy-3,14-dioxo-3,4,12,14-
tetrahydro-1H-pyrano[3′,4′:6,7]indolizino[1,2-b]quinolin9-yl 1,4′-bipiperidine-1′-carboxylate; 

Irinotecan EP  Impurity - E - (4S)-4,11-diethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7]-indolizino[1,2-b]quinoline-3,14(4H,12H)-dione ; (11-ethyl-9-hydroxycamptothecin) ; (S)-4,11-Diethyl-4,9-dihydroxy-1H-pyrano(3`,4`:6,7)indolizino(1,2-b)quinoline-3,14(4H,12H)-dione;Irinotecan USP Related Compound B ;

Irinotecan EP  Impurity - L - (4R)-4,11-diethyl-4-hydroxy-3,14-dioxo-3,4,12,14- tetrahydro-1H-pyrano[3′,4′:6,7]indolizino[1,2-b]quinolin9-yl 1,4′-bipiperidine-1′-carboxylate ; 

Irinotecan EP  Impurity - M - (4S)-4,11-diethyl-4,12-dihydroxy-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3′,4′:6,7]indolizino[1,2-b]quinolin9-yl 1,4′-bipiperidine-1′-carboxylate;
 

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Purity:

Above - 95.0%

Technical Data:

We will provide complete documentation support for every Standard Material. All analytical reports such as ¹H NMR, ¹³C NMR, Mass, FT-IR, HPLC Purity/GC Purity/QNMR Purity, Water content by KF/ Loss on Drying/TGA (Thermo-gravimetric Analysis). Certificate of Analysis with potency report. Each Standard Material SER (Structure Elucidation Report) with NMR, Mass, IR spectral interpretation. This whole analytical document can be included in eCTD, ANDA, DMF submissions to regulatory agencies.

Irinotecan CRS is used in chromatographic analysis to ensure system suitability by providing accurate peak identification and proper peak resolution. It acts as a standard reference to verify retention time, peak shape, and overall chromatographic performance, ensuring reliable and precise quality control of pharmaceutical formulations.