باب
Irinotecan
رقم CAS
Irinotecan Hydrochloride Trihydrate STD - 136572-09-3 : IMP - C - 947687-02-7 : IMP - E - 86639-52-3 : IMP - L - 1255644-71-3 : IMP - M - 185336-12-3
رقم CAS البديل
Free Base - 97682-44-5 , HCL - 100286-90-6
الصيغة الجزيئية
Irinotecan Hydrochloride Trihydrate STD - C33H45ClN4O9 : IMP - C -C35H42N4O6 : IMP - E - C22H20N2O5 : IMP - L - C33H38N4O6 : IMP - M - C33H38N4O7;
وزن جزيئي
Irinotecan Hydrochloride Trihydrate STD - 677.18 g/mol : IMP - C - 614.73 g/mol : IMP - E - 392.4 g/mol : IMP - L - 586.68 g/mol : IMP - M - 602.68 g/mol;
مرادف

Irinotecan Hydrochloride Trihydrate - (S)-4,11-Diethyl-4-hydroxy-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3`,4`:6,7]indolizino[1,2-b]quinolin-9-yl [1,4`-bipiperidine]-1`-carboxylate hydrochloride trihydrate ; (4S)-4,11-Diethyl-4-hydroxy-3,14-dioxo-3,4,12,14-;

Irinotecan EP  Impurity - C  -  (4S)-4,8,11-triethyl-4-hydroxy-3,14-dioxo-3,4,12,14-
tetrahydro-1H-pyrano[3′,4′:6,7]indolizino[1,2-b]quinolin9-yl 1,4′-bipiperidine-1′-carboxylate; 

Irinotecan EP  Impurity - E - (4S)-4,11-diethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7]-indolizino[1,2-b]quinoline-3,14(4H,12H)-dione ; (11-ethyl-9-hydroxycamptothecin) ; (S)-4,11-Diethyl-4,9-dihydroxy-1H-pyrano(3`,4`:6,7)indolizino(1,2-b)quinoline-3,14(4H,12H)-dione;Irinotecan USP Related Compound B ;

Irinotecan EP  Impurity - L - (4R)-4,11-diethyl-4-hydroxy-3,14-dioxo-3,4,12,14- tetrahydro-1H-pyrano[3′,4′:6,7]indolizino[1,2-b]quinolin9-yl 1,4′-bipiperidine-1′-carboxylate ; 

Irinotecan EP  Impurity - M - (4S)-4,11-diethyl-4,12-dihydroxy-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3′,4′:6,7]indolizino[1,2-b]quinolin9-yl 1,4′-bipiperidine-1′-carboxylate;
 

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Purity:

Above - 95.0%

Technical Data:

We will provide complete documentation support for every Standard Material. All analytical reports such as ¹H NMR, ¹³C NMR, Mass, FT-IR, HPLC Purity/GC Purity/QNMR Purity, Water content by KF/ Loss on Drying/TGA (Thermo-gravimetric Analysis). Certificate of Analysis with potency report. Each Standard Material SER (Structure Elucidation Report) with NMR, Mass, IR spectral interpretation. This whole analytical document can be included in eCTD, ANDA, DMF submissions to regulatory agencies.

Irinotecan CRS is used in chromatographic analysis to ensure system suitability by providing accurate peak identification and proper peak resolution. It acts as a standard reference to verify retention time, peak shape, and overall chromatographic performance, ensuring reliable and precise quality control of pharmaceutical formulations.