Catégorie
Orphenadrine
Numéro CAS
Orphenadrine STD - 341-69-5 ; IMP - A - 5472-13-9 ; IMP - B - 131-58-8 ; IMP - C - 17349-96-1 ; IMP - D - 58-73-1 ; IMP - F - 19804-27-4 ;
Autre numéro CAS
341-69-5 (Citrate) , 83-98-7 (Free Base)
Formule moléculaire
Orphenadrine STD - C18H24ClNO ; IMP - A - C14H14O ; IMP - B - C14H12O; IMP - C - C16H19NO ; IMP - D - C17H21NO ; IMP - F - C18H23NO ;
Masse moléculaire
Orphenadrine STD - 305.84 g/mol ; IMP - A - 198.26 g/mol; IMP - B - 196.25 g/mol; IMP - C - 241.33 g/mol ; IMP - D - 255.4 g/mol ; IMP - F - 269.39 g/ mol ;
Synonyme

Orphenadrine STD - beta-Dimethylaminoethyl 2-methylbenzhydryl ether hydrochloride; N,N-Dimethyl-2-(2-methylbenzhydryloxy)ethylamine hydrochloride; o-Methyldiphenhydramine hydrochloride; 

Orphenadrine EP Impurity -A - (RS)-(2-Methylphenyl)phenylmethanol ; 2-Methylbenzhydrol ; (2-Methylphenyl)phenylmethanol; Phenyl(2-tolyl)methanol; o-Methylbenzhydrol; α-(2-Methylphenyl)benzenemethanol; α-(2-Methylphenyl)benzyl Alcohol; 2-Methylbenzhydrol ; 

Orphenadrine EP Impurity - B - (2-Methylphenyl)phenylmethanone; 2-Methylbenzophenone; Phenyl(o-tolyl)methanone; 

Orphenadrine EP Impurity - C - 2-[(2-Methylphenyl)phenylmethoxy]-ethanamine; 2-[(o-Methyl-α-phenylbenzyl)oxy]-ethylamine; 2-(Phenyl(o-tolyl)methoxy)ethan-1-amine; N,N-Didemethylorphenadrine;  

Orphenadrine EP Impurity - D -  2-(Diphenylmethoxy)-N,N-dimethylethanamine ; Diphenhydramine ; 2-benzhydryloxy-N,N-dimethylethanamine ;

Orphenadrine EP Impurity - F - (RS)-N,N-Dimethyl-2-[(4-methylphenyl)phenylmethoxy]ethanamine ; N,N-dimethyl-2-[(4-methylphenyl)phenylmethoxy]ethanamine;;

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Purity:

Above - 95.0%

Technical Data:

We will provide complete documentation support for every Standard Material. All analytical reports such as ¹H NMR, ¹³C NMR, Mass, FT-IR, HPLC Purity/GC Purity/QNMR Purity, Water content by KF/ Loss on Drying/TGA (Thermo-gravimetric Analysis). Certificate of Analysis with potency report. Each Standard Material SER (Structure Elucidation Report) with NMR, Mass, IR spectral interpretation. This whole analytical document can be included in eCTD, ANDA, DMF submissions to regulatory agencies.

Orphenadrine can be used in peak identification for Capillary Electrophoresis (CE) or Chromatography-Related Separation (CRS) applications due to its characteristic retention/migration behavior, serving as a reference or internal standard.