Catégorie
Ciclosporin (Cyclosporine)
Numéro CAS
108027-46-9
Formule moléculaire
C63H113N11O12
Masse moléculaire
1216.66 g/mol
Synonyme

(3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-15,30-diethyl-33-[(E,1R,2R)-1-hydroxy-2-methylhex-4-enyl]-1,4,7,10,12,19,25,28-octamethyl-6,9,18,24-tetrakis(2-methylpropyl)-3,21-di(propan-2-yl)-1,4,7,10,13,16,19,22,25,28,31-undecazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undecone; Abu1-ciclosporin A; 1,11-Anhydro[D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl-N-methyl-L-[(1S,N-methyl-Lleucyl-L-valyl-N-methyl-L-leucyl-L-2-aminobutanoic acid]; 1,11-anhydro[D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl-[(2S,3R,4R,6E)-3-hydroxy-4-methyl-2-(methylamino)oct-6-enoyl-(2S)-2-aminobutanoyl-N-methylglycyl-N-methyl-L-leucyl-L-valyl-N-methyl-L-leucyl-(2S)-2-aminobutanoic acid]; Ciclosporin V

Mots-clés
Intermediates
Impurities
Metabolites.
Pharmaceutical Standards
Fine Chemicals
Peptides
slide.1
Purity:

Above - 95.0%

Technical Data:

We will provide complete documentation support for every Standard Material. All analytical reports such as ¹H NMR, ¹³C NMR, Mass, FT-IR, HPLC Purity/GC Purity/QNMR Purity, Water content by KF/ Loss on Drying/TGA (Thermo-gravimetric Analysis). Certificate of Analysis with potency report. Each Standard Material SER (Structure Elucidation Report) with NMR, Mass, IR spectral interpretation. This whole analytical document can be included in eCTD, ANDA, DMF submissions to regulatory agencies.

Cyclosporin EP Impurity E is a specified related substance in the European Pharmacopoeia used as a reference impurity to monitor and limit cyclosporin-related impurities, helping ensure the drug’s purity, quality, and safety.