Catégorie
Methotrexate
Numéro CAS
Methotrexate STD-59-05-2; 133073-73-1(Hydrate Salt);NA(Disodium Tetrahydrate): IMP-F-51865-79-3; NA(disodium salt)
Formule moléculaire
Methotrexate STD-C20H22N8O5: IMP-F-C20H22N8O5
Masse moléculaire
Methotrexate STD-454.44: IMP-F-454.44
Synonyme

Methotrexate STD-(2S)-2-[[4-[(2,4-diaminopteridin-6-yl)methyl-methylamino]benzoyl]amino]pentanedioic acid; (+)-Amethopterin; Antifolan; CL 14377; EMT 25299; Emtexate; Ledertrexate; MTX; L-Metatrexan; Methylaminopterin; Mexate; NSC 740; R 9985; Rheumatrex; Trexall; N-[4-[[(2,4-Diamino-6-pteridinyl)methyl]methylamino]benzoyl]-L-glutamic Acid; 4-Amino-N10-methylpteroylglutamic Acid; 4-Amino-N10-methylfolic Acid; l-Glutamic acid, N-[4-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]-; (S)-2-(4-{[(2,4-Diaminopteridin-6-yl)methyl](methyl)amino}benzamido)pentanedioic Acid; (USP)

Methotrexate EP-Impurity-F-(2R)-2-[[4-[(2,4-diaminopteridin-6-yl)methyl-methylamino]benzoyl]amino]pentanedioic acid; (R)-Methotrexate

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Purity:

Above - 95.0%

Technical Data:

We will provide complete documentation support for every Standard Material. All analytical reports such as ¹H NMR, ¹³C NMR, Mass, FT-IR, HPLC Purity/GC Purity/QNMR Purity, Water content by KF/ Loss on Drying/TGA (Thermo-gravimetric Analysis). Certificate of Analysis with potency report. Each Standard Material SER (Structure Elucidation Report) with NMR, Mass, IR spectral interpretation. This whole analytical document can be included in eCTD, ANDA, DMF submissions to regulatory agencies.

Methotrexate for System Suitability CRS is a certified reference substance used to verify the proper performance of analytical systems, particularly in chromatographic methods like HPLC. It ensures system parameters such as resolution, precision, and sensitivity meet pharmacopeial requirements, confirming that methotrexate assays produce accurate and reliable results.