Embryo-fetal toxicity refers to harmful effects on a developing embryo or fetus due to exposure to certain substances, such as medications, chemicals, or environmental factors.
Fluid retention, also known as water retention, occurs when excess fluid builds up in the body's tissues, causing swelling often in the hands, feet, ankles, or legs.
Mineralocorticoids are hormones produced by the outer layer of the adrenal glands that help control the body's balance of salt, water, and electrolytes.
Hypoglycemia occurs when blood sugar levels fall too low, depriving the body—and especially the brain—of its main energy source. A blood glucose level under 70 mg/dL is generally considered hypoglycemic.
Hypokalaemia is a medical condition in which the potassium level in the bloodstream is too low. Potassium is essential for proper muscle function, nerve activity, and maintaining a regular heartbeat. A drop in potassium can lead to symptoms like tiredness, muscle cramps, weakness, and, in more serious cases, dangerous heart rhythm disturbances.
Ventricular arrhythmias refer to irregular heartbeats that begin in the heart's lower chambers, known as the ventricles. These disturbances affect the heart’s electrical signaling and can interfere with its ability to pump blood effectively.
Prostate-Specific Antigen (PSA) is a protein made by both healthy and cancerous cells in the prostate gland. While its primary role is in semen, where it helps with sperm motility, small amounts are also found in the bloodstream.
metastatic castration-resistant prostate cancer (mCRPC) and metastatic high-risk castration-sensitive prostate cancer (mCSPC or mHSPC) refer to two distinct clinical stages of advanced prostate cancer. Both involve metastasis, but they differ in how the cancer responds to hormonal therapy.