باب
Lovastatin
رقم CAS
Lovastatin STD - 75330-75-5 : IMP- A - 73573-88-3 : IMP - B - 75225-51-3 : IMP - C - 109273-98-5 : IMP - D - 149756-62-7 : IMP - F -1048973-04-1;
الصيغة الجزيئية
Lovastatin STD - C24H36O5 : IMP- A - C23H34O5 : IMP - B - C24H38O6 : IMP - C - C24H34O4 : IMP - D - C48H72O10 : IMP - F - C24H34O5
وزن جزيئي
Lovastatin STD - 404.5 g/mol : IMP- A - 390.51 g/mol : IMP - B - 422.55 g/mol : IMP - C - 386.52 g/mol : IMP - D - 809.08 g/mol : IMP - F - 402.52 g/mol
مرادف

Lovastatin - (1S,3R,7S,8S,8aR)-8-[2-[(2R,4R)-4-hydroxy-6-oxooxan-2-yl]ethyl]-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl (2S)-2-methylbutanoate; (S)-(1S,3R,7S,8S,8aR)-8-(2-((2R,4R)-4-hydroxy-6-oxotetrahydro-2H-pyran-2-yl)ethyl)-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl 2-methylbutanoate;(2S)-2-Methylbutanoic Acid (1S,3R,7S,8S,8aR)-1,2,3,7,8,8a-Hexahydro-3,7-dimethyl-8-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1-naphthalenyl Ester ;

Lovastatin EP Impurity - A - (1S,7S,8S,8aR)-8-[2-[(2R,4R)-4-hydroxy-6-oxotetrahydro-2H-pyran-2-yl]ethyl]-7-methyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl (2S)-2-methylbutanoate ; Compactin ; Pravastatin Deshydroxy Impurity;Mevastatin;

Lovastatin EP Impurity - B - (3R,5R)-7-[(1S,2S,6R,8S,8aR)-2,6-Dimethyl-8-[[(2S)-2-methylbutanoyl]oxy]-1,2,6,7,8,8ahexahydronaphthalen-1-yl]-3,5-dihydroxyheptanoic Acid; Lovastatin Hydroxy Acid;3R,5R)-7-((1S,2S,6R,8S,8aR)-2,6-Dimethyl-8-(((S)-2-methylbutanoyl)oxy)-1,2,6,7,8,8a-hexahydronaphthalen-1-yl)-3,5-dihydroxyheptanoic Acid; 

Lovastatin EP Impurity - C - (1S,3R,7S,8S,8aR)-3,7-Dimethyl-8-[2-[(2R)-6-oxo-3,6-dihydro-2H-pyran-2-yl]ethyl]-1,2,3,7,8,8a-hexahydronaphthalen-1-yl (2S)-2-methylbutanoate; (2S)-2-Methylbutanoic Acid (1S,3R,7S,8S,8aR)-8-[2-[(2R)-3,6-Dihydro-6-oxo-2H-pyran-2-yl]ethyl]-1,2,3,7,8,8a-hexahydro-3,7-dimethyl-1-naphthalenyl Ester ;(1S,3R,7S,8S,8aR)-3,7-Dimethyl-8-(2-((R)-6-oxo-3,6-dihydro-2H-pyran-2-yl)ethyl)-1,2,3,7,8,8a-hexahydronaphthalen-1-yl (S)-2-methylbutanoate; Dehydro Lovastatin;

Lovastatin EP Impurity - D - (2R,4R)-2-[2-[(1S,2S,6R,8S,8aR)-2,6-dimethyl-8-[[(2S)-2-methylbutanoyl]oxy]-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]ethyl]-6-oxotetrahydro-2H-pyran-4-yl (3R,5R)-7-[(1S,2S,6R,8S,8aR)-2,6-dimethyl-8-[[(2S)-2-methylbutanoyl]oxy]-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]-3,5-dihydroxyheptanoate ; LovastatinDimer;

Lovastatin EP Impurity - F - (1S,3R,7S,8S,8aR)-8-[2-[(2R,4R)-4-Hydroxy-6-oxotetrahydro-2H-pyran-2-yl]ethyl]-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl (2Z)-2-methylbut-2-enoate ;  2',3'-Didehydro Lovastatin ; 

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يمكن استخدام لوفاستاتين في الدراسات الكروماتوغرافية، مثل كروماتوغرافيا السائل عالي الأداء (HPLC)، لتحديد الذروة وتحديد كميتها في مراقبة جودة المستحضرات الصيدلانية. كما يُستخدم كمركب مرجعي في دراسات الاحتفاظ المقارن (CRS) لضمان دقة فصل المواد ذات الصلة والكشف عنها.