Category
Bortezomib
CAS Number
NA
Molecular Formula
C19H24N4O3
Molecular Weight
356.4 g/mol
Synonym

N-((R)-1-(((R)-1-Hydroxy-3-methylbutyl)amino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide

Keywords
boron derivatives
Fine Chemicals
Enzyme inhibitors
Pharmaceutical Standards
Intermediates
Chiral standards
slide.1
Purity:

Above - 95.0%

Technical Data:

We will provide complete documentation support for every Standard Material. All analytical reports such as ¹H NMR, ¹³C NMR, Mass, FT-IR, HPLC Purity/GC Purity/QNMR Purity, Water content by KF/ Loss on Drying/TGA (Thermo-gravimetric Analysis). Certificate of Analysis with potency report. Each Standard Material SER (Structure Elucidation Report) with NMR, Mass, IR spectral interpretation. This whole analytical document can be included in eCTD, ANDA, DMF submissions to regulatory agencies.

Bortezomib Impurity 2 (R,R-isomer) is a stereoisomeric impurity of Bortezomib in which both chiral centers have the R configuration. Although the R,R configuration is the biologically active form of bortezomib, in the context of this impurity, it may arise as an unintended by-product during synthesis or handling. Its presence is monitored in pharmaceutical formulations to ensure consistency, potency, and safety of the drug.