Category
Bortezomib
CAS Number
114457-94-2
Alternate CAS Number
1093959-79-5(Magnesium Salt);1093959-75-1(Sodium - Salt)
Molecular Formula
C14H13N3O3
Molecular Weight
271.27g/mol
Synonym

(2S)-3-phenyl-2-(pyrazine-2-carbonylamino)propanoic acid; N-Pyrazinylcarbonyl-L-phenylalanine; Bortezomib Acid Impurity; (pyrazine-2-carbonyl)-L-phenylalanine; N-(2-pyrazinylcarbonyl)-L-phenylalanine; (S)-3-Phenyl-2-(pyrazine-2-carboxamido)propanoic acid; Bortezomib Acid Analog (USP)

Keywords
Fine Chemicals
Pharmaceutical Standards
Metabolites.
Impurities
Intermediates
slide.1
Purity:

Above - 95.0%

Technical Data:

We will provide complete documentation support for every Standard Material. All analytical reports such as ¹H NMR, ¹³C NMR, Mass, FT-IR, HPLC Purity/GC Purity/QNMR Purity, Water content by KF/ Loss on Drying/TGA (Thermo-gravimetric Analysis). Certificate of Analysis with potency report. Each Standard Material SER (Structure Elucidation Report) with NMR, Mass, IR spectral interpretation. This whole analytical document can be included in eCTD, ANDA, DMF submissions to regulatory agencies.

Bortezomib acid analog is a derivative of Bortezomib in which the boronic acid moiety remains but the molecule is modified from the parent active drug form. These analogs are studied for their role as proteasome inhibitors and are important in pharmaceutical research, particularly in anticancer drug development, as bortezomib itself is widely used in the treatment of multiple myeloma.