Category
Adagrasib
CAS Number
58246-54-1
Molecular Formula
C₅H₁₀N₂O₂
Molecular Weight
130.15 g/mol
Synonym

[(2S)-1-nitrosopyrrolidin-2-yl]methanol; 2-Pyrrolidinemethanol, 1-nitroso-, (2S); 2-Pyrrolidinemethanol, 1-nitroso-, (S); 1-Nitroso-2(S)-pyrrolidinemethanol

Keywords
Metabolites.
Pharmaceutical Standards
Intermediates
Fine Chemicals
Nitrosamine Standards
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Purity:

Above - 95.0%

Technical Data:

We will provide complete documentation support for every Standard Material. All analytical reports such as ¹H NMR, ¹³C NMR, Mass, FT-IR, HPLC Purity/GC Purity/QNMR Purity, Water content by KF/ Loss on Drying/TGA (Thermo-gravimetric Analysis). Certificate of Analysis with potency report. Each Standard Material SER (Structure Elucidation Report) with NMR, Mass, IR spectral interpretation. This whole analytical document can be included in eCTD, ANDA, DMF submissions to regulatory agencies.

Adagrasib Nitroso Impurity-9 is a nitroso-type impurity associated with Adagrasib. It contains a nitroso (–NO) functional group that can form during the drug’s synthesis, handling, or storage. Like other nitroso impurities, it is strictly monitored and controlled at trace levels because of potential carcinogenic concerns, ensuring the final drug product remains safe and meets regulatory quality standards.