Category
Adagrasib
CAS Number
NA
Molecular Formula
C₂₀H₂₂ClN₇O
Molecular Weight
411.89 g/mol
Synonym

(S)-2-(4-(7-Benzyl-2-chloro-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-4-yl)-1-nitrosopiperazin-2-yl)acetonitrile 

Keywords
Pharmaceutical Standards
Intermediates
Fine Chemicals
Nitrosamine Standards
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Purity:

Above - 95.0%

Technical Data:

We will provide complete documentation support for every Standard Material. All analytical reports such as ¹H NMR, ¹³C NMR, Mass, FT-IR, HPLC Purity/GC Purity/QNMR Purity, Water content by KF/ Loss on Drying/TGA (Thermo-gravimetric Analysis). Certificate of Analysis with potency report. Each Standard Material SER (Structure Elucidation Report) with NMR, Mass, IR spectral interpretation. This whole analytical document can be included in eCTD, ANDA, DMF submissions to regulatory agencies.

Adagrasib Nitroso Impurity-4 is another nitroso-type impurity associated with Adagrasib. It contains a nitroso (–NO) group that can form during manufacturing or degradation. Like other nitroso impurities, it is carefully monitored and controlled at very low levels due to potential safety concerns, especially possible carcinogenic risk.