Cimetidine is a histamine H₂-receptor antagonist widely used in the treatment of peptic ulcer disease, gastroesophageal reflux disease, and other acid-related disorders. It works by reducing gastric acid secretion through competitive inhibition of H₂ receptors in the stomach lining. Cimetidine was one of the first H₂ blockers introduced into clinical practice and has played a significant role in the management of acid-peptic conditions. In addition to its therapeutic use, cimetidine is well characterized chemically and pharmacologically. It is commonly analyzed in pharmaceutical quality control laboratories to ensure product quality and safety. Accurate analytical methods, including chromatographic techniques, are essential for its identification and quantification.
