Category
Cimetidine
CAS Number
Cimetidine STD - 51481-61-9 : IMP-B- 138035-55-9 ; IMP-C- 77076-18-7 ; IMP-D-70172-53-1 ; IMP-E - 54237-72-8; IMP-G- 31857-31-5 ; IMP-H- 74886-59-2;
Molecular Formula
Cimetidine STD - C10H16N6S ; IMP-B-C10H15N5OS ; IMP-C-C10H18N6OS ; IMP-D-C9H17N5S ; IMP-E - C10H16N6OS ; IMP-G- C4H8N4 ; IMP-H- C10H18N8S2 ;
Molecular Weight
Cimetidine STD - 252.3 g/mol ; IMP-B-253.3 g/mol; IMP-C- 270.4 g/mol ; IMP-D- 227.3 g/mol ; IMP-E - 268.3g/mol; IMP-G- 112.1 g/mol ; IMP-H- 314.4 g/mol ;
Synonym

Cimetidine - 2-Cyano-1-methyl-3-[2-[[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl]ethyl]guanidine ;2-Cyano-1-methyl-3-[2-[[(5-methylimidazol-4-yl)methyl]thio]ethyl]guanidine;

Cimetidine EP Impurity B - Methyl 3-cyano-1-[2-[[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl]ethyl]carbamimidate ; Cimetidine Methoxy Analog ;

Cimetidine EP Impurity C - 1-[(Methylamino)[[2-[[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl]ethyl]amino]methylidene]urea ;

Cimetidine EP Impurity D - 1-Methyl-3-[2-[[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl]ethyl]guanidine ;

Cimetidine EP Impurity E - 2-Cyano-1-methyl-3[2-[[(5-methyl-1H-imidazol-4-yl)methyl]sulfinyl]ethyl]guanidine; Cimetidine Sulfoxide ;

Cimetidine EP Impurity G - 2-Cyano-1,3-dimethylguanidine ;

Cimetidine EP Impurity H - 1,1′-(disulfanediyldiethylene)bis(2-cyano-3-methylguanidine) ;Cimetidine Disulfane Impurity ;

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Purity:

Above - 95.0%

Technical Data:

We will provide complete documentation support for every Standard Material. All analytical reports such as ¹H NMR, ¹³C NMR, Mass, FT-IR, HPLC Purity/GC Purity/QNMR Purity, Water content by KF/ Loss on Drying/TGA (Thermo-gravimetric Analysis). Certificate of Analysis with potency report. Each Standard Material SER (Structure Elucidation Report) with NMR, Mass, IR spectral interpretation. This whole analytical document can be included in eCTD, ANDA, DMF submissions to regulatory agencies.

Cimetidine CRS is used in system suitability testing to verify the performance of the chromatographic system by ensuring consistent retention time and peak shape. It is employed to evaluate parameters such as theoretical plates, tailing factor, and %RSD, confirming the system is suitable for routine analysis.