باب
Nilotinib
رقم CAS
Nilotinib STD - 641571-10-0 ; IMP - E - 2119583-26-3; IMP - F - 2119583-24-1 ; IMP -G - 917392-54-2;
رقم CAS البديل
923288-90-8(MonoHCl Monohydrate Salt);923288-95-3(HCl Salt);
الصيغة الجزيئية
Nilotinib STD- C28H22F3N7O ; C28H25ClF3N7O2 (MonoHCl Monohydrate Salt) ; C28H23ClF3N7O (HCl Salt);IMP - E - C27H20F3N7O ; IMP - F - C29H24F3N7O; IMP -G - C18H16N4O2 ;
وزن جزيئي
Nilotinib STD - 529.52 g/mol ; IMP - E - 515.49 g/mol ; IMP - F - 515.49 g/mol; IMP -G - 320.35 g/mol
مرادف

Nilotinib - 4-Methyl-N-[3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl]-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]benzamide;Tasigna; 

Nilotinib EP Impurity - E - N-(3-(1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)-4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)benzamide; Desmethylimidazole Nilotinib ; N-[3-(1H-Imidazol-1-yl)-5-(trifluoromethyl)phenyl]-4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]benzamide; 

Nilotinib EP  Impurity - F - N-[3-(4-Ethyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl]-4-methyl-3-{[4-(pyridin-3-yl)pyrimidin-2-yl]amino}benzamide ; N-(3-(4-Ethyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)-4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)benzamide ;Benzamide ; 

Nilotinib EP Impurity - G - Methyl 4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)benzoate ; Methyl 4-Methyl-3-[[4-(pyridin-3-yl)pyrimidin-2-yl]amino]benzoate;4-Methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]benzoic Acid Methyl Ester;                                                         

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Nilotinib for system suitability CRS is used as a reference standard to verify the performance of chromatographic systems, ensuring accurate, precise, and reliable analysis of nilotinib in pharmaceutical formulations.