باب
Regorafenib
رقم CAS
755037-03-7
الصيغة الجزيئية
C21H15ClF4N4O3
وزن جزيئي
482.82 g/mol
مرادف

4-[4-[[[[4-Chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]-3-fluorophenoxy]-N-methyl-2-pyridinecarboxamide;4-[4-[N'-(4-Chloro-3-trifluoromethylphenyl)ureido]-3-fluorophenoxy]pyridine-2-carboxylic Acid Methylamide;4-[4-[[[[4-Chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]-3-fluorophenoxy]-N-methyl-2-pyridinecarboxamide;4-[4-[N'-(4-Chloro-3-trifluoromethylphenyl)ureido]-3-fluorophenoxy]pyridine-2-carboxylic Acid Methylamide;

الكلمات الرئيسية
Amines
Aromatics
Pharmaceutical Standards
Intermediates
Fine Chemicals
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Regorafenib is an oral multi-kinase inhibitor used to treat metastatic colorectal cancer, gastrointestinal stromal tumors, and hepatocellular carcinoma after failure of prior therapies. It works by blocking multiple signaling pathways involved in tumor growth, angiogenesis, and metastasis. Common side effects include fatigue, hypertension, diarrhea, and hand–foot skin reactions.