Category
Calcium folinate
CAS Number
58-05-9
Alternate CAS Number
1492-18-8(Ca Salt);6035-45-6(Ca Pentahydrate Salt)
Molecular Formula
C20H23N7O7
Molecular Weight
473.45 g/mol
Synonym

(2S)-2-[[4-[(2-amino-5-formyl-4-oxo-3,6,7,8-tetrahydropteridin-6-yl)methylamino]benzoyl]amino]pentanedioic acid; leucovorin; (4-(((2-amino-5-formyl-4-oxo-3,4,5,6,7,8-hexahydropteridin-6-yl)methyl)amino)benzoyl)-L-glutamic acid; L-Glutamic acid, N-[4-[[(2-amino-5-formyl-3,4,5,6,7,8-hexahydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]; 5-Formyltetrahydropteroylglutamic acid; N5-Formyltetrahydrofolic Acid

Keywords
Chiral standards
Heterocycles
Pharmaceutical Standards
Intermediates
Fine Chemicals
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Purity:

Above - 95.0%

Technical Data:

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Folinic acid (also known as leucovorin) is an active form of folic acid (vitamin B9) that does not require enzymatic reduction in the body. It plays an important role in DNA synthesis and cell division. Clinically, it is used to reduce the toxic effects of methotrexate therapy (leucovorin rescue), enhance the effectiveness of 5-fluorouracil in cancer treatment, and treat certain types of folate deficiency anemia. It is commonly available as calcium folinate for oral or injectable use.