Category
Bortezomib
CAS Number
1104011-35-9
Molecular Formula
C19H25BN4O4
Molecular Weight
384.24 g/mol
Synonym

[(1R)-1-[[(2S)-3-phenyl-2-(pyrazine-2-carbonylamino)propanoyl]amino]pentyl]boronic acid; Bortezomib N-Pentyl Impurity; B-[(1R)-1-[[(2S)-1-Oxo-3-phenyl-2-[(2-pyrazinylcarbonyl)amino]propyl]amino]pentyl]boronic Acid; 1-[[(2S)-1-Oxo-3-phenyl-2-[(pyrazinylcarbonyl) amino]propyl]amino] pentylboronic Acid

Keywords
Impurities
Metabolites.
Pharmaceutical Standards
Intermediates
Fine Chemicals
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Purity:

Above - 95.0%

Technical Data:

We will provide complete documentation support for every Standard Material. All analytical reports such as ¹H NMR, ¹³C NMR, Mass, FT-IR, HPLC Purity/GC Purity/QNMR Purity, Water content by KF/ Loss on Drying/TGA (Thermo-gravimetric Analysis). Certificate of Analysis with potency report. Each Standard Material SER (Structure Elucidation Report) with NMR, Mass, IR spectral interpretation. This whole analytical document can be included in eCTD, ANDA, DMF submissions to regulatory agencies.

Desisobutyl-n-butyl Bortezomib is a structural analog of Bortezomib in which the original isobutyl group is replaced with an n-butyl group. This modification can alter the molecule’s pharmacokinetics, stability, or proteasome-binding properties. Such derivatives are often studied as impurities, degradation products, or experimental analogs to evaluate their activity and safety compared with the parent drug.