Category
Bortezomib
CAS Number
390800-88-1
Molecular Formula
C57H69B3N12O9
Molecular Weight
1098.7 g/mol
Synonym

N,N',N''-((2S,2'S,2''S)-(((1R,1'R,1''R)-(1,3,5,2,4,6-Trioxatriborinane-2,4,6-triyl)tris(3-methylbutane-1,1-diyl))tris(azanediyl))tris(1-oxo-3-phenylpropane-1,2-diyl))tris(pyrazine-2-carboxamide); N-[(2S)-1-[[(1R)-1-[4,6-bis[(1R)-3-methyl-1-[[(2S)-3-phenyl-2-(pyrazine-2-carbonylamino)propanoyl]amino]butyl]-1,3,5,2,4,6-trioxatriborinan-2-yl]-3-methylbutyl]amino]-1-oxo-3-phenylpropan-2-yl]pyrazine-2-carboxamide; Bortezomib Impurity 10; (2S,2`S)-2,2`,2``-(((1R,1'R)-(1,3,5,2,4,6-Trioxatriborinane-2,4,6-triyl)tris(3-methylbutane-1,1-diyl))tris(azanediyl))tris(3-phenyl-N-(pyrazine-2-carbonyl)propanamide); Bortezomib ((1R,2S)-Bortezomib)

Keywords
boron derivatives
Chiral standards
Intermediates
slide.1
Purity:

Above - 95.0%

Technical Data:

We will provide complete documentation support for every Standard Material. All analytical reports such as ¹H NMR, ¹³C NMR, Mass, FT-IR, HPLC Purity/GC Purity/QNMR Purity, Water content by KF/ Loss on Drying/TGA (Thermo-gravimetric Analysis). Certificate of Analysis with potency report. Each Standard Material SER (Structure Elucidation Report) with NMR, Mass, IR spectral interpretation. This whole analytical document can be included in eCTD, ANDA, DMF submissions to regulatory agencies.

Bortezomib trimer is an oligomeric form of Bortezomib in which three bortezomib molecules are chemically linked together. This trimer can form as a degradation product or during chemical reactions and is considered an impurity. Its presence is controlled in pharmaceutical formulations because it can affect the drug’s stability, solubility, and therapeutic efficacy.