Category
Bortezomib
CAS Number
289472-80-6
Molecular Formula
C14H14N4O2
Molecular Weight
270.3 g/mol
Synonym

N-[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]pyrazine-2-carboxamide; (S)-N-(1-Amino-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide; N-[(1S)-2-amino-2-oxo-1-(phenylmethyl)ethyl]pyrazinecarboxamide; Pyrazinecarboxamide, N-[(1S)-2-amino-2-oxo-1-(phenylmethyl)ethyl]-; Bortezomib Amide Analog (S isomer)

Keywords
Fine Chemicals
Pharmaceutical Standards
Metabolites.
Impurities
Intermediates
slide.1
Purity:

Above - 95.0%

Technical Data:

We will provide complete documentation support for every Standard Material. All analytical reports such as ¹H NMR, ¹³C NMR, Mass, FT-IR, HPLC Purity/GC Purity/QNMR Purity, Water content by KF/ Loss on Drying/TGA (Thermo-gravimetric Analysis). Certificate of Analysis with potency report. Each Standard Material SER (Structure Elucidation Report) with NMR, Mass, IR spectral interpretation. This whole analytical document can be included in eCTD, ANDA, DMF submissions to regulatory agencies.

Bortezomib Impurity A is a known degradation or synthetic by-product of Bortezomib. It arises during manufacturing or storage and can differ slightly in chemical structure from the active drug, potentially affecting potency or stability. Regulatory guidelines require its identification, quantification, and control to ensure the safety and efficacy of bortezomib formulations.