Category
Avapritinib
Avapritinib
CAS Number
1703793-34-3
Molecular Formula
C₂₆H₂₇FN₁₀
Molecular Weight
498.57 g/mol
Catalogue Number
MLS-AVP-STD
Synonym

(1S)-1-(4-Fluorophenyl)-1-(2-{4-[6-(1-methyl-1H-pyrazol-4-yl)pyrrolo[2,1-f][1,2,4]triazin-4-yl]piperazin-1-yl}pyrimidin-5-yl)ethan-1-amine; (S)-1-(4-fluorophenyl)-1-(2-(4-(6-(1-methyl-1H-pyrazol-4-yl)pyrrolo[2,1-f][1,2,4]triazin-4-yl)piperazin-1-yl)pyrimidin-5-yl)ethan-1-amine;

Keywords
High-Quality Pharmaceutical Reference Standards
Intermediates
Pharmaceutical Standards
Fine Chemicals
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Purity:

Above - 95.0%

Technical Data:

We will provide complete documentation support for every Standard Material. All analytical reports such as ¹H NMR, ¹³C NMR, Mass, FT-IR, HPLC Purity/GC Purity/QNMR Purity, Water content by KF/ Loss on Drying/TGA (Thermo-gravimetric Analysis). Certificate of Analysis with potency report. Each Standard Material SER (Structure Elucidation Report) with NMR, Mass, IR spectral interpretation. This whole analytical document can be included in eCTD, ANDA, DMF submissions to regulatory agencies.

Avapritinib API (CAS No. 1703793-34-3), with a Molecular Formula of C₂₆H₂₇FN₁₀ and Molecular Weight of 498.57 g/mol, is a small-molecule tyrosine kinase inhibitor (TKI) targeting KIT and PDGFRA mutations, used in the treatment of certain gastrointestinal stromal tumors (GIST) and systemic mastocytosis. Manasa Life Sciences, a pharmaceutical API and analytical reference standards manufacturer and supplier in India, offers Avapritinib API and Avapritinib Analytical Reference Standards for oncology pharmaceutical research, drug development, API manufacturers, CROs, CDMOs, and quality control laboratories. This Avapritinib API Reference Standard supports HPLC analysis, LC-MS/MS characterization, API purity testing, impurity profiling, related substances analysis, stability studies, pharmaceutical formulation development, and analytical method validation. Its analytical applications are relevant to applicable ICH guidelines, EMA regulatory requirements, European Pharmacopoeia (EP), and United States Pharmacopeia (USP) analytical standards. Product-specific Certificate of Analysis (COA), SDS/MSDS, and analytical characterization reports may be available upon request, subject to availability.