Category
Atropine
CAS Number
Atropine STD - 51-55-8: IMP - A - 500-55-0 : IMP - D - 55869-99-3 : IMP - E - 949092-65-3 : IMP - F - 51-34-3 : IMP - G - 21956-47-8 :
Alternate CAS Number
5908-99-6 (Atropine Sulfate Monohydrate)
Molecular Formula
Atropine STD - C17H23NO3, IMP - A - C17H21NO2 : IMP - D - C17H23NO4 : IMP - E - C17H23NO4: IMP - F - C17H21NO4 : IMP - G - C17H23NO3 :
Molecular Weight
Atropine STD - 289.37 g/mol ,IMP - A - 271.36 g/mol : IMP - D - 305.37 g/mol : IMP - E - 305.37 g/mol : IMP - F - 303.36 g/mol : IMP - G - 289.38 g/mol:
Synonym

Atropine -(RS)-(8-methyl-8-azabicyclo[3.2.1]oct-3-yl) 3-hydroxy-2-phenylpropanoate; Benzeneacetic acid, α-(hydroxymethyl)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester, endo-(±)-; 1αH,5αH-Tropan-3α-ol (±)-tropate (ester) (USP);

Atropine EP Impurity A - (1R,3r,5S)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl2-phenylpropenoate (apoatropine) ; Apoatropin; Apohyoscyamin; Apohyoscyamine; Atropamin; Atropamine;Atropyltropeine;

Atropine EP Impurity D - [(1R,3S,5R,6S)-6-hydroxy-8-methyl-8-azabicyclo[3.2.1]octan-3-yl] (2S)-3-hydroxy-2-phenylpropanoate ; 6-hydroxyhyoscyamine ; Benzeneaceticacid,alpha-(hydroxymethyl)-,(1R,3S,5R,6S)-6-hydroxy-8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester,(alphaS) ; (-)-6beta-Hydroxyhyoscyamine;(-)-Anisodamine;6-Hydroxyhyoscyamine;

Atropine EP Impurity E - (1S,3R,5S,6RS)-6-hydroxy-8-methyl-8-azabicyclo-[3.2.1]oct-3-yl (2S)-3-hydroxy-2-phenylpropanoate ; 7-Hydroxy Hyoscyamine (USP) ;

Atropine EP Impurity F - (1R,2R,4S,5S,7s)-9-methyl-3-oxa-9-azatricyclo-[3.3.1.02,4]non-7-yl (2S)-3-hydroxy-2-phenylpropanoate : hyoscine ;

Atropine EP Impurity G - (1R,3r,5S)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl(2RS)-2-hydroxy-3-phenylpropanoate ; littorine ;

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Purity:

Above - 95.0%

Technical Data:

We will provide complete documentation support for every Standard Material. All analytical reports such as ¹H NMR, ¹³C NMR, Mass, FT-IR, HPLC Purity/GC Purity/QNMR Purity, Water content by KF/ Loss on Drying/TGA (Thermo-gravimetric Analysis). Certificate of Analysis with potency report. Each Standard Material SER (Structure Elucidation Report) with NMR, Mass, IR spectral interpretation. This whole analytical document can be included in eCTD, ANDA, DMF submissions to regulatory agencies.

Atropine CRS is used in system suitability and peak identification to confirm the correct retention time and identity of atropine in analytical methods like HPLC. It ensures accurate and reliable detection of the drug in samples by serving as a reference standard.