Category
Atorvastatin
CAS Number
1105067-88-6(ca salt)
Alternate CAS Number
1428118-38-0(Na Salt); 501121-34-2(Freebase)
Molecular Formula
C66H68CaF2N4O10
Molecular Weight
1155.34 g/mol
Catelogue Number
MLS-ATR-RC-E
Synonym

Atorvastatin Enantiomer Calcium Salt; Atorvastatin Calcium Impurity E; (3S,5S)-Atorvastatin Calcium Salt; Atorvastatin Acid - Impurity E (Calcium Salt); (3S,5S)-7-[2-(4-fluorophenyl)-3-phenyl-4-(phenylcarbamoyl)-5-(propan-2-yl)-1H-pyrrol-1-yl]-3,5-dihydroxyheptanoic Acid Sodium Salt; (βS,δS)-2-(4-Fluorophenyl)-β,δ-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrole-1-heptanoic Acid Calcium Salt; (3S,5S)-7-(2-(4-Fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl)-3,5-dihydroxyheptanoate Calcium; Calcium (3S,5S)-7-[2-(4-Fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl]-3,5-dihydroxyheptanoate (1:2); (3S,5S)-7-[3-(phenylcarbamoyl)-5-(4-fluorophenyl)-2-isopropyl-4-phenyl-1H-pyrrol-1-yl]-3,5-dihydroxyheptanoic acid, Calcium Salt ; Atorvastatin EP Impurity-E

Keywords
Impurities
Chiral standards
Intermediates
Metabolites.
Pharmaceutical Standards
Aromatics
Enzyme inhibitors
Fine Chemicals
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Atorvastatin Related Compound - E, also known as Atorvastatin EP Impurity E with CAS No: 1105067-88-6, is a pharmaceutical impurity reference standard associated with the synthesis and stereochemical profile of atorvastatin. Chemical Name: calcium bis((3S,5S)-7-[2-(4-fluorophenyl)-3-phenyl-4-(phenylcarbamoyl)-5-propan-2-ylpyrrol-1-yl]-3,5-dihydroxyheptanoate); Molecular Formula: C66H68CaF2N4O10; Molecular Weight: 1155.34 g/mol. It is widely used in atorvastatin impurity characterization, impurity profiling, analytical method development, and quality control in pharmaceutical laboratories. This enantiomeric impurity is monitored for accurate atorvastatin impurity quantification and effective control of atorvastatin process-related impurities, supporting the identification of USP/EP impurities in atorvastatin and ensuring compliance with regulatory impurity limits.

Manasa Life Sciences, based in Hyderabad, supplies high-quality Atorvastatin impurity reference standards to pharmaceutical manufacturers and research organizations worldwide, with distribution across Asia, Europe, Africa, the GCC, and the UAE. The company maintains full traceability, certified reference standards, and strict Good Documentation Practices (GDP). Using advanced techniques such as HPLC, LC-MS/MS, and GC-MS, the team supports impurity characterization, analytical method validation, and impurity risk assessment, helping companies comply with global regulatory guidelines established by the FDA, EMA, USP, EP, and ICH.