Category
Abemaciclib
CAS Number
NA
Molecular Formula
C₂₇H₃₂F₂N₈O
Molecular Weight
522.59 g/mol
Synonym

5-((4-ethylpiperazin-1-yl)methyl)-2-((5-fluoro-4-(4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazol-6-yl)pyrimidin-2-yl)amino)pyridine 1-oxide ; Abemaciclib Pyridine N-Oxide Impurity;

Keywords
Pharmaceutical Intermediates
Impurities
Aromatic
Amines
Impurities manufacturer and Suppliers in Hyderabad india
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Purity:

Above - 95.0%

Technical Data:

We will provide complete documentation support for every Standard Material. All analytical reports such as ¹H NMR, ¹³C NMR, Mass, FT-IR, HPLC Purity/GC Purity/QNMR Purity, Water content by KF/ Loss on Drying/TGA (Thermo-gravimetric Analysis). Certificate of Analysis with potency report. Each Standard Material SER (Structure Elucidation Report) with NMR, Mass, IR spectral interpretation. This whole analytical document can be included in eCTD, ANDA, DMF submissions to regulatory agencies.

Abemaciclib Pyridine N-oxide Impurity is a degradation or process-related impurity formed when the pyridine ring in abemaciclib is oxidized at the nitrogen atom. This impurity is usually controlled at trace levels in the drug substance because it may affect purity, stability, and safety, though it is generally less genotoxic than nitrosamine impurities.