Tadalafil is an oral medication primarily used to treat Erectile Dysfunction and symptoms of Benign Prostatic Hyperplasia; it belongs to a class of drugs called phosphodiesterase type 5 (PDE5) inhibitors, which work by increasing blood flow to specific areas of the body through smooth muscle relaxation. It was originally developed in the 1990s by the biotechnology company ICOS Corporation in partnership with Eli Lilly and Company, and after clinical trials demonstrated its effectiveness and longer duration of action compared to similar drugs, it was approved by the U.S. Food and Drug Administration in 2003 and marketed under the brand name Cialis, gaining popularity for its extended therapeutic window (up to 36 hours), which earned it the nickname “the weekend pill.”