Sucralose is a zero-calorie artificial sweetener widely used as a sugar substitute in food and beverages. It is derived from sucrose through selective chlorination, which replaces three hydroxyl groups with chlorine atoms, making it approximately 600 times sweeter than sugar. Unlike sugar, sucralose is not metabolized by the body for energy, contributing no calories to the diet. It is highly stable under heat and across a wide range of pH, making it suitable for cooking and baking. Sucralose does not promote tooth decay and is considered safe for people with diabetes due to its negligible effect on blood glucose levels. It is commonly found in soft drinks, chewing gum, baked goods, and tabletop sweeteners. Sucralose passes through the gastrointestinal tract largely unchanged, with most of it excreted in the feces. Regulatory agencies worldwide, including the FDA and EFSA, have approved sucralose as safe for human consumption. Its intense sweetness allows manufacturers to use very small amounts, reducing sugar content while maintaining taste. Overall, sucralose is a popular, stable, and safe alternative to sugar for calorie reduction and blood sugar management.