Prednisone is a synthetic corticosteroid widely used for its anti-inflammatory and immunosuppressive properties. Developed in the 1950s, it was created as a prodrug of prednisolone to improve oral bioavailability and reduce liver metabolism issues. Prednisone quickly became a cornerstone in the treatment of conditions such as asthma, autoimmune disorders, and various inflammatory diseases. Over the decades, it has remained a mainstay in clinical medicine due to its efficacy, versatility, and ability to be administered in both short-term and long-term therapies, making it one of the most commonly prescribed corticosteroids worldwide.
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