Buserelin is a synthetic peptide analog of gonadotropin-releasing hormone (GnRH) with high biological activity. It acts on the pituitary gland to initially stimulate and then suppress the release of luteinizing hormone and follicle-stimulating hormone. Due to this mechanism, buserelin is widely used in the management of hormone-dependent conditions. It is commonly prescribed in the treatment of prostate cancer to reduce testosterone levels. Buserelin is also used in the management of endometriosis and uterine fibroids. In reproductive medicine, it plays an important role in controlled ovarian stimulation protocols for in vitro fertilization. The drug is administered via nasal spray or injection, depending on the therapeutic indication. Buserelin helps regulate hormone levels in precocious puberty. It is well studied for its efficacy and safety in long-term hormonal therapy. Overall, buserelin is an important therapeutic agent in oncology and reproductive health.
