باب
حمض الفوسيديك
رقم CAS
حمض الفوسيديك - 6990-06-3؛ الشائبة A - 80445-74-5؛ الشائبة B - غير متوفر؛ الشائبة C - غير متوفر؛ الشائبة D - 3054708-76-5؛ الشائبة F - 1415035-94-7؛ الشائبة G - 4680-37-9؛ الشائبة H - 16711-91-4؛ الشائبة N - 13090-91-0
الصيغة الجزيئية
حمض الفوسيديك - C31H48O6؛ IMP-A- C31H50O8؛ IMP-B- C31H48O7؛ IMP-C- C31H48O7؛ IMP-D-؛ IMP-F- C31H46O7؛ IMP-G- C31H46O6؛ IMP-H- C31H46O6؛ IMP-N- C29H46O5
وزن جزيئي
حمض الفوسيديك - 516.71؛ IMP-A - 550.72؛ IMP-B - 532.71 جم/مول؛ IMP-C - 532.71؛ IMP-D - 532.71 جم/مول؛ IMP-F - 530.69 جم/مول؛ IMP-G - 514.69 جم/مول؛ IMP-H - 514.7 جم/مول؛ IMP-N - 474.7 جم/مول
مرادف

Fusidic acid - (3alpha,4alpha,8alpha,9beta,11alpha,13alpha,147beta,167beta,17Z)-16-(Acetyloxy)-3,11-dihydroxy-29-nordammara-17(20),24-dien-21-oic Acid

Fusidic acid EP Impurity A - (3α,4α,8α,9β,11α,13α,14β,16β,17Z)-16-(Acetyloxy)-3,11,24,25-tetrahydroxy-29-nordammar-17(20)-en-21-oic Acid; 24,25-Dihydroxyfusidic Acid; 24,25-dihydroxyfusidic Acid;

Fusidic acid EP Impurity B - (3R,4S,5S,8S,9S,10S,11R,13R,14S,16S,Z)-3,11-Dihydroxy-17-((R)-6-hydroxy-7,7-dimethyl-2-oxooxepan-3-ylidene)-4,8,10,14-tetramethylhexadecahydro-1H-cyclopenta[a]phenanthren-16-yl Acetate;ent-(17Z)-3β,11β-Dihydroxy-17-[(6SR)-6-hydroxy-7,7-dimethyl-2-oxooxepan-3- ylidene]-4β,8,14-trimethyl-18-nor-5β,10α-androstan-16α-yl Acetate;

Fusidic acid EP Impurity C - (3R,4S,5S,8S,9S,10S,11R,13R,14S,16S,Z)-3,11-Dihydroxy-17-((R)-6-(2-hydroxypropan-2-yl)-2-oxodihydro-2H-pyran-3(4H)-ylidene)-4,8,10,14-tetramethylhexadecahydro-1H-cyclopenta[a]phenanthren-16-yl Acetate

Fusidic acid EP Impurity D - (3R,4S,5S,8S,9S,10S,11R,13R,14S,16S,Z)-3,11-Dihydroxy-17-((S)-6-(2-hydroxypropan-2-yl)-2-oxodihydro-2H-pyran-3(4H)-ylidene)-4,8,10,14-tetramethylhexadecahydro-1H-cyclopenta[a]phenanthren-16-yl Acetate ; ent-(17Z)-3beta,11beta-Dihydroxy-17-[(6R)-6-(1-hydroxy-1-methylethyl)-2-oxodihydro-2H-pyran-3(4H)-ylidene]-4beta,8,14-trimethyl-18-nor-5beta,10alpha-androstan-16alpha-yl acetate;(24S)-24,25-Dihydro-24,25-dihydroxyfusidic acid 21,24-lactone; Fusidic Acid Impurity D;

Fusidic acid EP Impurity F - 26-Oxofusidic Acid;(2Z,5E)-2-((3R,4S,5S,8S,9S,10S,11R,13R,14S,16S)-16-acetoxy-3,11-dihydroxy-4,8,10,14-tetramethyldodecahydro-1H-cyclopenta[a]phenanthren-17(2H,10H,14H)-ylidene)-6-methyl-7-oxohept-5-enoic acid; Ent-(17Z,24EZ)-16alpha-(acetyloxy)-3beta,11beta-dihydroxy-4beta,8,14-trimethyl-26-oxo-18-nor-5beta,10alpha-cholesta-17(20),24-dien-21-oic acid;

Fusidic acid EP Impurity G - (4alpha,8alpha,9beta,11alpha,13alpha,14beta,16beta,17Z)-16-(Acetyloxy)-11-hydroxy-3-oxo-29-nordammara-17(20),24-dien-21-oic Acid; Ent-(17Z)-16α-(acetyloxy)-11β-hydroxy-4β,8,14-trimethyl-3-oxo-18-nor-5β,10α-cholesta-17(20),24-dien-21-oic acid;

Fusidic acid EP Impurity H - (3alpha,4alpha,8alpha,9beta,13alpha,14beta,16beta,17Z)-16-(Acetyloxy)-3-hydroxy-11-oxo-29-nordammara-17(20),24-dien-21-oic acid; Ent-(17Z)-16α-(acetyloxy)-3β-hydroxy-4β,8,14-trimethyl-11-oxo-18-nor-5β,10α-cholesta-17(20),24-dien-21-oic acid

Fusidic acid Impurity N - (Z)-6-Methyl-2-((3R,4S,5S,8S,9S,10S,11R,13R,14S,16S)-3,11,16-trihydroxy-4,8,10,14-tetramethylhexadecahydro-17H-cyclopenta[a]phenanthren-17-ylidene)hept-5-enoic acid

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يُستخدم حمض الفوسيديك (CRS) كمعيار مرجعي كيميائي لتحديد القمم (peaks) في التحليل الكروماتوغرافي، وذلك بهدف تأكيد وجود حمض الفوسيديك في المستحضرات الصيدلانية؛ إذ يضمن ذلك دقة التحديد والنوعية والامتثال لمتطلبات مراقبة الجودة المنصوص عليها في دساتير الأدوية.