Non-nutritive sweeteners (NNS), also known as artificial or zero-calorie sweeteners, are substances used to provide sweetness without adding significant calories to food or beverages. They are much sweeter than regular sugar, so only a very small amount is needed to achieve the desired taste. Unlike table sugar, NNS contribute little or no energy to the diet, making them a popular choice for people who want to reduce their calorie intake. These sweeteners also have a glycemic index of zero or close to zero, meaning they do not cause a rapid rise in blood glucose levels after consumption. For this reason, they are widely used in products intended for people with diabetes and those following low-carbohydrate diets. Common examples include aspartame, sucralose, saccharin, acesulfame potassium, and stevia. Non-nutritive sweeteners are commonly found in diet soft drinks, sugar-free desserts, chewing gum, yogurt, and many processed foods. They help people enjoy sweet-tasting foods while limiting sugar consumption. Research has shown that, when consumed within the recommended acceptable daily intake (ADI), these sweeteners are considered safe by food safety authorities. However, they should be used as part of a balanced diet rather than as a substitute for healthy eating habits. Choosing foods with non-nutritive sweeteners can support weight management and blood sugar control when combined with an overall healthy lifestyle.