Migraine acute migraine attacks are sudden episodes of moderate to severe headache, often characterized by throbbing pain on one side of the head and accompanied by symptoms such as nausea, vomiting, and sensitivity to light, sound, or smell. These attacks result from activation of the trigeminovascular system and release of neuropeptides such as CGRP, leading to neurogenic inflammation and pain. Treatment aims to relieve symptoms rapidly and includes analgesics, nonsteroidal anti-inflammatory drugs (NSAIDs), triptans, CGRP receptor antagonists, and antiemetics, depending on the severity of the attack.