Category
Voriconazole
CAS Number
86404-63-9
Molecular Formula
C₁₀H₇F₂N₃O
Molecular Weight
223.18 g/mol
Synonym

Fluconazole Keto Impurity; 1-(2,4-Difluorophenyl)-2-(1H-1,2,4-triazol-1-yl)-ethanone; Voriconazole Triazole Acetophenone Impurity; Fluconazole EP Impurity E; Voriconazole Impurity A (IP); Voriconazole Related Compound C (USP)

Keywords
Amines
Aromatics
Heterocycles
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Voriconazole EP Impurity A is a specified related substance listed in the European Pharmacopoeia (EP) for voriconazole, a triazole antifungal drug used to treat serious fungal infections. This impurity forms during the synthesis or degradation of voriconazole and is carefully monitored because pharmaceutical impurities can affect the safety, quality, and stability of the medicine. In pharmaceutical analysis, EP Impurity A is used as a reference standard during quality control testing to ensure that voriconazole products meet regulatory purity limits set by pharmacopeial standards.