Category
Nitroso Amines
CAS Number
NA
Molecular Formula
C18H18N2O2
Molecular Weight
294.4 g/mol
Synonym

N-(3-(Dibenzo[b,e]oxepin-11(6H)-ylidene)propyl)-N-methylnitrous amide; N-Nitroso Nordoxepin; N-(3-(Dibenzo[b,e]oxepin-11(6H)-ylidene)propyl)-N-methylnitrous amide; (E)-N-(3-(dibenzo[b,e]oxepin-11(6H)-ylidene)propyl)-N-methylnitrous amide; N-Nitroso Doxepin EP Impurity C

Keywords
Impurity Standards
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N-Nitroso Desmethyl (E)-Doxepin is a nitrosamine impurity that may form during the manufacturing or storage of doxepin, an antidepressant and anxiolytic medication. Like other nitrosamines, it is monitored because of its potential carcinogenic risk, not because it has any therapeutic or industrial purpose. Its relevance is limited to pharmaceutical quality control, impurity identification, and ensuring that doxepin products comply with regulatory safety limits.