Category
Nitrosamine Impurities
CAS Number
26360-21-4
Molecular Formula
C₁₉H₁₈N₈O₇
Molecular Weight
470.4 g/mol
Synonym

(4-(((2-Amino-4-oxo-4,8-dihydropteridin-6-yl)methyl)(nitroso)amino)benzoyl)-L-glutamic Acid; N-Nitroso Folinic Acid Impurity C; Glutamic acid, N-nitroso-N-pteroyl, L-; Nitrosofolic acid; L-Glutamic acid, N-[4-[[(2-amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-N-nitroso; (2S)-2-[[4-[(2-amino-4-oxo-3H-pteridin-6-yl)methyl-nitrosoamino]benzoyl]amino]pentanedioic acid

Keywords
Intermediates
Impurities
Metabolites.
Pharmaceutical Standards
Fine Chemicals
Nitrosamine Standards
Nitrosamine Standards manufacturers and Suppliers in Hyderabad India
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N‑Nitroso-Folic Acid is a nitrosamine impurity derived from folic acid, an essential B-vitamin crucial for DNA synthesis, cellular growth, and metabolic functions. This impurity forms when a nitroso group (–N=O) bonds to a nitrogen atom in folic acid. Its chemical name is N‑Nitroso-Folic Acid, with a CAS Number of 26360-21-4; molecular formula of C₁₉H₁₈N₈O₇ and an approximate molecular weight of 470.4 g/mol. As a nitrosamine, it is subject to global regulatory monitoring due to the potential mutagenic and carcinogenic risks associated with nitrosamine compounds.

Manasa Life Sciences manufactures nitrosamine impurities in Hyderabad, India, supplying markets across Asia, Europe, Africa, the GCC, and the UAE. The company ensures reliable delivery, full traceability, and compliance with Good Documentation Practices (GDP) for nitrosamine impurities. In addition, Manasa Life Sciences supports comprehensive nitrosamine-control programs by providing certified reference standards, conducting thorough risk assessments, and developing and validating highly sensitive LC-MS/MS and GC-MS analytical methods. These services enable precise detection, quantification, and management of nitrosamine impurities, whether theoretically predicted, synthesis-related, or degradation-derived, helping manufacturers comply with USP-relevant guidelines, meet global regulatory standards, and ensure patient safety.