Category
Losartan
CAS Number
IMP-G- 76-84-6 : IMP-J(RC-B)- 1006062-27-6 : IMP-K(RC-C)- 114798-36-6 : IMP-L(RC-D)- 230971-71-8: IMP-M(RC-E)- 230971-72-9
Molecular Formula
IMP-G-C19H16O: IMP-J(RC-B)- C24H25ClN6O2: IMP-K(RC-C)- C22H21ClN6O: IMP-L(RC-D)- C44H44Cl2N12O: IMP-M(RC-E)- C44H44Cl2N12O
Molecular Weight
IMP-G- 260.3: IMP-J(RC-B)- 465.0: IMP-K(RC-C)- 420.9: IMP-L(RC-D)- 827.8: IMP-M(RC-E)- 827.8
Synonym

Losartan EP Impurity G (Triphenylmethanol)

Losartan EP Impurity J ([2-Butyl-4-chloro-1-[[2′-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl]-1H-imidazol-5-yl]methyl acetate; Losartan USP Related Compound B)

Losartan EP Impurity K (2-Butyl-4-chloro-1-[[2′-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl]-1H-imidazol-5-carbaldehyde; Losartan USP Related Compound C)

Losartan EP Impurity L ([2-Butyl-1-[[2′-[1-[[2-butyl-4-chloro-1-[[2′-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl]-1H-imidazol-5-yl]methyl]-1H-tetrazol-5-yl]biphenyl-4-yl]methyl]-4-chloro-1H-imidazol-5-yl]methanol; Losartan USP Related Compound D)

Losartan EP Impurity M ([2-Butyl-1-[[2′-[2-[[2-butyl-4-chloro-1-[[2′-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl]-1H-imidazol-5-yl]methyl]-2H-tetrazol-5-yl]biphenyl-4-yl]methyl]-4-chloro-1H-imidazol-5-yl]methanol; Losartan USP Related Compound E)

Losartan for system suitability CRS

Losartan for system suitability CRS is a certified reference standard used in HPLC method validation to ensure the performance of the chromatographic system. It helps verify system suitability parameters such as resolution, tailing factor, theoretical plates, and retention time. Losartan CRS complies with USP, EP, and IP standards and is essential for assay, impurity profiling, stability studies, and regulatory submissions like ANDA and DMF filings.