Category
Levothyroxine
CAS Number
1628720-66-0
Molecular Formula
C15H11ClI3NO4
Molecular Weight
685.42 g/mol
Synonym

(2S)-2-amino-3-[4-(3-chloro-4-hydroxy-5-iodophenoxy)-3,5-diiodophenyl]propanoic acid;(S)-2-amino-3-(4-(3-chloro-4-hydroxy-5-iodophenoxy)-3,5-diiodophenyl)propanoic acid;O-(4-Hydroxy-3-chloro-5-iodophenyl)-3,5-diiodo-L-tyrosine;Levothyroxine Chloro Impurity

Keywords
Amines
Aromatics
Heterocycles
Pharmaceutical Standards
Intermediates
Fine Chemicals
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Purity:

Above - 95.0%

Technical Data:

We will provide complete documentation support for every Standard Material. All analytical reports such as ¹H NMR, ¹³C NMR, Mass, FT-IR, HPLC Purity/GC Purity/QNMR Purity, Water content by KF/ Loss on Drying/TGA (Thermo-gravimetric Analysis). Certificate of Analysis with potency report. Each Standard Material SER (Structure Elucidation Report) with NMR, Mass, IR spectral interpretation. This whole analytical document can be included in eCTD, ANDA, DMF submissions to regulatory agencies.

Levothyroxine EP Impurity B is another specified related substance in the European Pharmacopoeia for levothyroxine. It is a degradation or synthetic impurity of levothyroxine, monitored to ensure the API’s purity and quality, and is quantified using validated analytical methods like HPLC.