Category
Etravirine
CAS Number
Etravirine STD - 269055-15-4 : IMP - C - 1398507-09-9 : IMP - D - 939431-68-2
Molecular Formula
Etravirine STD - C20H15BrN6O : IMP - C - C11H7BrClN5 : IMP - D - C20H16N6O
Molecular Weight
Etravirine STD -435.28 g/mol : IMP - C - 324.6 g/mol : IMP - D - 356.38 g/mol
Synonym

Etravirine - 4-[[6-Amino-5-bromo-2-[(4-cyanophenyl)amino]-4-pyrimidinyl]oxy]-3,5-dimethyl-benzonitrile : 4-[6-Amino-5-bromo-2-(4-cyanoanilino)pyrimidin-4-yl]oxy-3,5-dimethylbenzonitrile;

Etravirine EP Impurity C - 4-[(4-Amino-5-bromo-6-chloropyrimidin-2-yl)amino]benzonitrile ; 3-Amino bromo Impurity ;

Etravirine EP Impurity D - 5-Desbromo Etravirine ; Benzonitrile,4-[[6-amino-2-[(4-cyanophenyl)amino]-4-pyrimidinyl]oxy]-3,5-dimethyl ; (4-{[6-Amino-2-{(4-cyanophenyl)amino}pyrimidin-4-yl]oxy}-3,5-dimethylbenzonitrile) ;

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Purity:

Above - 95.0%

Technical Data:

We will provide complete documentation support for every Standard Material. All analytical reports such as ¹H NMR, ¹³C NMR, Mass, FT-IR, HPLC Purity/GC Purity/QNMR Purity, Water content by KF/ Loss on Drying/TGA (Thermo-gravimetric Analysis). Certificate of Analysis with potency report. Each Standard Material SER (Structure Elucidation Report) with NMR, Mass, IR spectral interpretation. This whole analytical document can be included in eCTD, ANDA, DMF submissions to regulatory agencies.

Etravirine is used as a Chemical Reference Standard (CRS) for system suitability testing to verify the accuracy, precision, and reproducibility of analytical methods. Its well-characterized purity and stability ensure reliable assessment of chromatographic system performance during routine quality control analysis.