Category
Etravirine
CAS Number
Etravirine STD - 269055-15-4 : IMP - A - 2240161-92-4 : IMP - B -1704730-70-0
Molecular Formula
Etravirine STD - C20H15BrN6O : IMP - A - C25H24BrN7O2 : IMP - B - C29H21BrN6O2
Molecular Weight
Etravirine STD - 435.28 g/mol : IMP - A - 534.4 g/mol : IMP - B - 565.4 g/mol
Synonym

Etravirine - 4-[[6-Amino-5-bromo-2-[(4-cyanophenyl)amino]-4-pyrimidinyl]oxy]-3,5-dimethyl-benzonitrile : 4-[6-Amino-5-bromo-2-(4-cyanoanilino)pyrimidin-4-yl]oxy-3,5-dimethylbenzonitrile;

Etravirine EP Impurity A - 4-((5-Bromo-6-(4-cyano-2,6-dimethylphenoxy)-2-((4-cyanophenyl)amino)pyrimidin-4-yl)(methyl)amino)butanamide ; Etravirine Butanamide Analog :

Etravirine EP Impurity B - 4,4'-[[5-Bromo-2-(4-cyanoanilino)pyrimidine-4,6-diyl]bis(oxy)]bis(3,5-dimethylbenzonitrile) ; Bis(3,5-Dimethylbenzonitrile), 4,4'-((5-bromo-2-((4-cyanophenyl)amino)pyrimidine-4,6-diyl)bis(oxy));

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Purity:

Above - 95.0%

Technical Data:

We will provide complete documentation support for every Standard Material. All analytical reports such as ¹H NMR, ¹³C NMR, Mass, FT-IR, HPLC Purity/GC Purity/QNMR Purity, Water content by KF/ Loss on Drying/TGA (Thermo-gravimetric Analysis). Certificate of Analysis with potency report. Each Standard Material SER (Structure Elucidation Report) with NMR, Mass, IR spectral interpretation. This whole analytical document can be included in eCTD, ANDA, DMF submissions to regulatory agencies.

Etravirine is used as a Chemical Reference Standard (CRS) for peak identification to confirm the retention time and identity of etravirine in chromatographic analysis. Its certified purity ensures accurate and reliable identification during method validation and routine quality control.