Category
Dihydroergotamine
CAS Number
Dihydroergotamine STD - 511-12-6: IMP-A-113-15-5:IMP-B-3609-19-6 :IMP-C-2881077-62-7:IMP-D-5550-75-4:IMP-E-17479-19-5 ;
Alternate CAS Number
6190-39-2 (Mesilate)
Molecular Formula
Dihydroergotamine STD-C33H37N5O5:IMP-A-C33H35N5O5:IMP-B-C34H39N5O5:IMP-C-C33H37N5O6:IMP-D-C33H37N5O5:IMP-E-C35H41N5O5;
Molecular Weight
Dihydroergotamine STD-583 g/mol:IMP-A-581.7 g/mol:IMP -B-597.7 g/mol:IMP-C-599.7 g/mol:IMP-D-583.7 g/mol:IMP-E-611.7 g/mol;
Synonym

Dihydroergotamine - (6aR,9R,10aR)-N-[(1S,2S,4R,7S)-7-benzyl-2-hydroxy-4-methyl-5,8-dioxo-3-oxa-6,9-diazatricyclo[7.3.0.02,6]dodecan-4-yl]-7-methyl-6,6a,8,9,10,10a-hexahydro-4H-indolo[4,3-fg]quinoline-9-carboxamide ;

Dihydroergotamine EP Impurity A - (6aR,9R)-N-[(2R,5S,10aS,10bS)-5-Benzyl-10b-hydroxy-2-methyl-3,6-dioxooctahydro-8H-oxazolo[3,2-a]pyrrolo[2,1-c]pyrazin-2-yl]-7-methyl-4,6,6a,7,8,9-hexahydroindolo[4,3-fg]quinoline-9-carboxamide ;

Dihydroergotamine EP Impurity B - (6aR,9R,10aR)-N-[(2R,5S,10aS,10bS)-5-Benzyl-2-ethyl-10b-hydroxy-3,6-dioxooctahydro-8H-oxazolo[3,2-a]pyrrolo[2,1-c]pyrazin-2-yl]-7-methyl-4,6,6a,7,8,9,10,10a-octahydroindolo[4,3-fg]quinoline-9-carboxamide ;  9,10-Dihydroergostine ;

Dihydroergotamine EP Impurity C - (6aR,9S,10aR)-N-[(2R,5S,10aS,10bS)-5-Benzyl-10b-hydroxy-2-methyl-3,6-dioxooctahydro-8H-oxazolo[3,2-a]pyrrolo[2,1-c]pyrazin-2-yl]-9-hydroxy-7-methyl-4,6,6a,7,8,9,10,10aoctahydroindolo[4,3-fg]quinoline-9-carboxamide ;

Dihydroergotamine EP Impurity D - (6aR,9R,10aR)-N-[(2S,5S,10aS,10bS)-5-Benzyl-10b-hydroxy-2-methyl-3,6-dioxooctahydro-8H-oxazolo[3,2-a]pyrrolo[2,1-c]pyrazin-2-yl]-7-methyl-4,6,6a,7,8,9,10,10aoctahydroindolo[4,3-fg]quinoline-9-carboxamide ;

Dihydroergotamine EP Impurity E - (6aR,9R,10aR)-N-[(2R,5S,10aS,10bS)-5-benzyl-10bhydroxy-2-(1-methylethyl)-3,6-dioxo-octahydro-8Hoxazolo[3,2-a]pyrrolo[2,1-c]pyrazin-2-yl]-7-methyl4,6,6a,7,8,9,10,10a-octahydroindolo[4,3-fg]quinoline-9-carboxamide ;

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Purity:

Above - 95.0%

Technical Data:

We will provide complete documentation support for every Standard Material. All analytical reports such as ¹H NMR, ¹³C NMR, Mass, FT-IR, HPLC Purity/GC Purity/QNMR Purity, Water content by KF/ Loss on Drying/TGA (Thermo-gravimetric Analysis). Certificate of Analysis with potency report. Each Standard Material SER (Structure Elucidation Report) with NMR, Mass, IR spectral interpretation. This whole analytical document can be included in eCTD, ANDA, DMF submissions to regulatory agencies.

Dihydroergotamine for peak identification in a CRS application means using a certified Dihydroergotamine reference standard to confirm and correctly identify the chromatographic peak of dihydroergotamine in your analytical method by matching the sample’s retention time and response to that of the authentic standard under the same conditions.