Category
Crisaborole
CAS Number
888967-63-3
Molecular Formula
C₁₄H₁₁NO₂
Molecular Weight
225.24 g/mol
Synonym

4-[3-(Hydroxymethyl)phenoxy]benzonitrile;Crisaborole Impurity 7;Benzonitrile, 4-(3-(hydroxymethyl)phenoxy)benzonitrile;4-[(1-hydroxy-3H-2,1-benzoxaborol-5-yl)oxy]benzoic acid;Crisaborole Impurity 52; Crisaborole Impurity 7; 4-[3-(hydroxymethyl)phenoxy]benzonitrile

Keywords
Pharmaceutical Standards
Intermediates
Fine Chemicals
Impurities
slide.1
Purity:

Above - 95.0%

Technical Data:

We will provide complete documentation support for every Standard Material. All analytical reports such as ¹H NMR, ¹³C NMR, Mass, FT-IR, HPLC Purity/GC Purity/QNMR Purity, Water content by KF/ Loss on Drying/TGA (Thermo-gravimetric Analysis). Certificate of Analysis with potency report. Each Standard Material SER (Structure Elucidation Report) with NMR, Mass, IR spectral interpretation. This whole analytical document can be included in eCTD, ANDA, DMF submissions to regulatory agencies.

Crisaborole Impurity A is a specified related impurity that can form during the synthesis or degradation of Crisaborole. It is typically monitored and controlled in pharmaceutical quality standards to ensure the safety, purity, and stability of the final drug product. Regulatory guidelines set acceptable limits for such impurities, and analytical methods like HPLC are commonly used for its detection and quantification.