Category
Chlorhexidine
CAS Number
Chlorhexidine STD - 55-56-1 ; IMP-A- 152504-08-0 ;IMP-B- 1308292-89-8; IMP-H- NA ;IMP-K- 1381962-77-1;IMP-N- 152504-10-4 ; IMP-O - 2508008-02-2;
Molecular Formula
Chlorhexidine STD - C22H30Cl2N10 ; IMP-A- C16H24ClN9 ;IMP-B- C16H26ClN9O ; IMP-H- C30H47Cl2N15 ;IMP-K- C22H29Cl2N9O;IMP-N- C15H25ClN8 ; IMP-O- C22H30Cl2N10 ;
Molecular Weight
Chlorhexidine STD - 505.5 g/mol; IMP-A- 377.9 g/mol ;IMP-B- 395.9 g/mol ; IMP-H- 688.7 g/mol;IMP-K- 506.44 g/mol ;IMP-N- 352.87 g/mol ; IMP-O-505.45 g/mol;
Synonym

Chlorhexidine - (1E)-2-[6-[[amino-[(E)-[amino-(4-chloroanilino)methylidene]amino]methylidene]amino]hexyl]-1-[amino-(4-chloroanilino)methylidene]guanidine;

Chlorhexidine EP Impurity A- 1-[amino-(4-chloroanilino)methylidene]-2-[6-[[amino-(cyanoamino)methylidene]amino]hexyl]guanidine;

Chlorhexidine EP Impurity B- N-[N-[6-[[N-[N-(4-chlorophenyl)carbamimidoyl]- carbamimidoyl]amino]hexyl]carbamimidoyl]urea;

Chlorhexidine EP Impurity H- 2-[6-[[amino-[[N'-[6-[[amino-[[amino-(4-chloroanilino)methylidene]amino]methylidene]amino]hexyl]carbamimidoyl]amino]methylidene]amino]hexyl]-1-[amino-(4-chloroanilino)methylidene]guanidine;

Chlorhexidine EP Impurity K- N-(4-Chlorophenyl)-N′-[N-[6-[[N-[N-(4-chlorophenyl)carbamimidoyl]carbamimidoyl]amino]hexyl]carbamimidoyl]urea ; 

Chlorhexidine EP Impurity N- 1-[6-(Carbamimidoylamino)hexyl]-5-(4-chlorophenyl)biguanide;

Chlorhexidine EP Impurity O- N1 -[6-[[N-[N-(2-chlorophenyl)carbamimidoyl]- carbamimidoyl]amino]hexyl]-N3 -(4-chlorophenyl)- imidodicarbonimidic diamide;

Purity:

Above - 95.0%

Technical Data:

We will provide complete documentation support for every Standard Material. All analytical reports such as ¹H NMR, ¹³C NMR, Mass, FT-IR, HPLC Purity/GC Purity/QNMR Purity, Water content by KF/ Loss on Drying/TGA (Thermo-gravimetric Analysis). Certificate of Analysis with potency report. Each Standard Material SER (Structure Elucidation Report) with NMR, Mass, IR spectral interpretation. This whole analytical document can be included in eCTD, ANDA, DMF submissions to regulatory agencies.

Chlorhexidine CRS is used as a reference standard for system suitability testing in chromatographic analytical methods. It ensures the accuracy, precision, and performance of the system during quality control and pharmaceutical analysis.