Category
Anlotinib
CAS Number
2205042-80-2
Molecular Formula
C₃₀H₂₈FN₃O₃
Molecular Weight
497.6 g/mol
Synonym

1-(((4-((3-Benzyl-4-fluoro-2-methyl-1H-indol-5-yl)oxy)-6-methoxyquinolin-7-yl)oxy)methyl)cyclopropan-1-amine; Cyclopropanamine, 1-[[[4-[[4-fluoro-2-methyl-3-(phenylmethyl)-1H-indol-5-yl]oxy]-6-methoxy-7-quinolinyl]oxy]Methyl]; 1-(((4-((3-benzyl-4-fluoro-2-methyl-1H-indol-5-yl)oxy)-6-methoxyquinolin-7-yl)oxy)methyl)cyclopropan-1-Amine; 1-[[[4-[[4-Fluoro-2-methyl-3-(phenylmethyl)-1H-indol-5-yl]oxy]-6-methoxy-7-quinolinyl]oxy]methyl]cyclopropanamine

Keywords
Pharmaceutical Standards
Intermediates
Fine Chemicals
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Purity:

Above - 95.0%

Technical Data:

We will provide complete documentation support for every Standard Material. All analytical reports such as ¹H NMR, ¹³C NMR, Mass, FT-IR, HPLC Purity/GC Purity/QNMR Purity, Water content by KF/ Loss on Drying/TGA (Thermo-gravimetric Analysis). Certificate of Analysis with potency report. Each Standard Material SER (Structure Elucidation Report) with NMR, Mass, IR spectral interpretation. This whole analytical document can be included in eCTD, ANDA, DMF submissions to regulatory agencies.

The benzyl impurity in Anlotinib is a trace by-product that can arise during its chemical synthesis, often from benzyl-protected intermediates or reagents. Although present in small amounts, it is important because it can affect the drug’s purity, safety, and stability. Monitoring and controlling this impurity is done using analytical techniques like HPLC or LC-MS to ensure the final pharmaceutical product meets regulatory quality standards.