Minocycline is a broad-spectrum antibiotic belonging to the tetracycline class, effective against a wide range of bacterial infections. It works by inhibiting bacterial protein synthesis, thereby preventing bacterial growth. Minocycline was first developed in the 1960s as a semi-synthetic derivative of tetracycline. It was introduced to improve oral absorption, tissue penetration, and a longer half-life compared to older tetracyclines. The drug gained popularity for treating acne, respiratory tract infections, urinary tract infections, and certain sexually transmitted infections. Its ability to penetrate the central nervous system also made it useful for treating some neurological infections. Over the years, minocycline has been studied for anti-inflammatory and neuroprotective properties. It is available in oral and intravenous formulations. The medication is widely prescribed due to its effectiveness and favorable pharmacokinetic profile. Today, minocycline remains an important antibiotic in both dermatology and general infectious disease treatment.
BRAND NAMES
- Minocin – Oral and intravenous formulations
- Solodyn – Extended-release oral tablets, often used for acne
- Dynacin – Oral capsules and tablets
- Arestin – Local delivery system for periodontal treatment
- CoreMino – Generic oral tablets
