Levocabastine is a second-generation antihistamine primarily used as a topical ocular and nasal treatment for allergic conditions, particularly allergic conjunctivitis and rhinitis. Chemically, it is a selective H1 receptor antagonist, which helps reduce the effects of histamine, such as itching, redness, and swelling. Levocabastine was developed in the 1980s as part of efforts to create more targeted antihistamines with fewer systemic side effects compared to first-generation drugs. Its introduction marked a significant advancement in allergy therapy, offering rapid relief with minimal sedation. Over time, levocabastine has become widely used in eye drops and nasal sprays, valued for its efficacy, safety, and convenience in managing localized allergic reactions.
