Furosemide is a potent loop diuretic widely used in the management of edema and hypertension associated with conditions such as heart failure, liver disease, and renal disorders. It was first synthesized in the early 1960s by researchers at Hoechst AG in Germany. Furosemide was developed as part of efforts to create more effective diuretics than thiazides. It rapidly gained clinical acceptance due to its strong and fast-acting diuretic effect. The drug works by inhibiting sodium and chloride reabsorption in the loop of Henle. Its introduction significantly improved the treatment of fluid overload states. Over time, furosemide became one of the most commonly prescribed diuretics worldwide. It remains an essential medicine in modern clinical practice.
BRAND NAMES
Lasix (Tablets, Oral Solution, Injection)
Furoscix (Subcutaneous Injection via On-Body Infusor)
Lasix ONYU (Subcutaneous Infusion)
Urex / Urex Forte
Frusol (Common in the UK)
