Elagolix is an orally active, non-peptide gonadotropin-releasing hormone (GnRH) receptor antagonist used in the treatment of hormone-dependent disorders. It works by suppressing pituitary gonadotropin secretion, leading to reduced ovarian estrogen production. This mechanism helps manage moderate to severe pain associated with endometriosis. Elagolix offers a rapid onset of action and flexible dosing compared to injectable GnRH therapies. By effectively controlling estrogen levels, it improves symptoms while allowing individualized treatment under medical supervision.

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CAS Number
832720-36-2
Alternate CAS Number
834153-87-6 (free base) ; 2390005-65-7 (HCl salt) ; 2254609-59-9 (K salt) ; 2390005-66-8 (TFA salt)