Desloratadine is a second-generation antihistamine used to relieve symptoms of allergic conditions such as allergic rhinitis and chronic urticaria (hives). It works by selectively blocking histamine H₁ receptors, thereby reducing symptoms like sneezing, itching, runny nose, and watery eyes. Desloratadine has a long duration of action and causes minimal sedation compared to first-generation antihistamines. It is taken orally and is generally well tolerated, making it suitable for daily use in allergy management.