Demeclocycline is a tetracycline antibiotic that is also used for its ability to reduce the action of antidiuretic hormone (ADH). In addition to treating certain bacterial infections, it is commonly prescribed in the management of syndrome of inappropriate antidiuretic hormone secretion (SIADH). Demeclocycline works by decreasing the responsiveness of the kidneys to ADH, thereby promoting water excretion and helping correct hyponatremia. It is taken orally and should be used under medical supervision due to potential side effects, including kidney toxicity and photosensitivity.
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