Category
Vildagliptin
Nitrosamine Impurities
CAS Number
3034601-47-0
Molecular Formula
C₁₇H₂₄N₄O₃
Molecular Weight
332.4 g/mol
Synonym

N-(2-((S)-2-Cyanopyrrolidin-1-yl)-2-oxoethyl)-N-(3-hydroxyadamantan-1-yl)nitrous amide; N-(2-((S)-2-cyanopyrrolidin-1-yl)-2-oxoethyl)-N-((1r,3R,5R,7S)-3-hydroxyadamantan-1-yl)nitrous amide; 2-Pyrrolidinecarbonitrile, 1-[2-[(3-hydroxytricyclo[3.3.1.13,7]dec-1-yl)nitrosoamino]acetyl]-, (2S); N-[2-[(2S)-2-cyanopyrrolidin-1-yl]-2-oxoethyl]-N-[(5S,7R)-3-hydroxy-1-adamantyl]nitrous amide

Keywords
Nitrosamine Standards manufacturers and Suppliers in Hyderabad India
Fine Chemicals
Nitrosamine Standards
Pharmaceutical Standards
Metabolites.
Impurities
Intermediates
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Vildagliptin N-nitroso vildagliptin is a nitrosamine impurity that can form during manufacturing or storage when vildagliptin or its intermediates react with nitrosating agents. Nitrosamine impurities are strictly monitored because many compounds in this class are considered potentially genotoxic and carcinogenic at certain levels. Therefore, regulatory guidelines require tight control and sensitive analytical testing (such as LC-MS/MS) to ensure that N-nitroso vildagliptin remains within acceptable safety limits in pharmaceutical products.