Category
Regorafenib
CAS Number
Regorafenib STD-755037-03-7; 1019206-88-2(Monohydrate Salt): FP-Impurity-A-2514957-39-0: IMP-C-1855006-12-0: IMP-D-2438857-80-6
Alternate CAS Number
1019206-88-2(Monohydrate Salt)
Molecular Formula
Regorafenib STD-C21H15ClF4N4O3: FP-Impurity-A-C16H16FN3O4: IMP-C-C20H18FN5O3: IMP-D-C27H22F2N6O5
Molecular Weight
Regorafenib STD-482.82: FP-Impurity-A-333.31: IMP-C-395.39: IMP-D-548.5
Synonym

Regorafenib STD-4-[4-[[4-chloro-3-(trifluoromethyl)phenyl]carbamoylamino]-3-fluorophenoxy]-N-methylpyridine-2-carboxamide; 4-[4-[[[[4-Chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]-3-fluorophenoxy]-N-methyl-2-pyridinecarboxamide;4-[4-[N'-(4-Chloro-3-trifluoromethylphenyl)ureido]-3-fluorophenoxy]pyridine-2-carboxylic Acid Methylamide

Regorafenib FP-Impurity-A-Ethyl (2-Fluoro-4-((2-(methylcarbamoyl)pyridin-4-yl)oxy)phenyl)carbamate

Regorafenib-IMP-C- 4-[3-fluoro-4-[[2-(methylcarbamoyl)pyridin-4-yl]amino]phenoxy]-N-methylpyridine-2-carboxamide: Regorafenib-IMP-D-4-[3-fluoro-4-[[2-fluoro-4-[[2-(methylcarbamoyl)-4-pyridinyl]oxy]phenyl]carbamoylamino]phenoxy]-N-methylpyridine-2-carboxamide  

Slide 1.GIF
Purity:

Above - 95.0%

Technical Data:

We will provide complete documentation support for every Standard Material. All analytical reports such as ¹H NMR, ¹³C NMR, Mass, FT-IR, HPLC Purity/GC Purity/QNMR Purity, Water content by KF/ Loss on Drying/TGA (Thermo-gravimetric Analysis). Certificate of Analysis with potency report. Each Standard Material SER (Structure Elucidation Report) with NMR, Mass, IR spectral interpretation. This whole analytical document can be included in eCTD, ANDA, DMF submissions to regulatory agencies.

Regorafenib for System Suitability CRS used to verify the performance of the chromatographic system by evaluating parameters like resolution, repeatability, and retention time during system suitability testing before sample analysis.