Category
Promethazine
CAS Number
Promethazine STD - : 60-87-7 : ;Impurity - A : 92-84-2 ;Impurity - B : 303-14-0 ;Impurity - C : 37707-23-6 ;
Alternate CAS Number
58-33-3(HCl Salt):27059-74-1(Maleate Salt)
Molecular Formula
Promethazine STD - : C17H20N2S ;Impurity - A : C12H9NS ;Impurity - B : C17H20N2S ;Impurity - C : C16H18N2S ;
Molecular Weight
Promethazine STD - : 284.43 g/mol ;Impurity - A : 199.27 g/mol ;Impurity - B : 284.42 g/mol ;Impurity - C : 270.39 g/mol ;
Synonym

Promethazine STD - N,N,Alpha-Trimethyl-10H-phenothiazine-10-ethanamine; (+/-)-Promethazine; N,N-dimethyl-1-(10H-phenothiazin-10-yl)propan-2-amine (USP)

Promethazine EP Impurity  A : 10H-Phenothiazine; Contaverm; Danikoropa; Dibenzo-1,4-thiazine; Dibenzothiazine; Feeno; Fenoverm; NSC 2037; Nemazene; Nexarbol; Orimon; Padophene; Penthazine; Phenegic; Phenoverm; Phenovis; Phenoxur; Phenthiazine; Phenzeen; Reconox; Thiodiphenylamine 

Promethazine EP Impurity  B : (2RS)-N,N-Dimethyl-2-(10H-phenothiazin-10-yl)propan-1-amine; N,N,β-Trimethyl-10H-phenothiazine-10-ethanamine; Phenothiazine, 10-[2-(dimethylamino)-1-methylethyl]; 10-(2-Dimethylaminoisopropyl)phenothiazine; Isomethazine; Isophenergan; N-[2-(Dimethylamino)-1-methylethyl]phenothiazine; Prothiazin; Isopromethazine (IP); N,N-Dimethyl-2-(10H-phenothiazin-10-yl)propan-1-amine; Promethazine Related Compound B (USP-HCl) 

Promethazine EP Impurity C : N,α-Dimethyl-10H-phenothiazine-10-ethanamine; N-Desmethyl Promethazine; Desmethyl Promethazine, N-Methyl-1-(10H-phenothiazin-10-yl)propan-2-amine (USP);

Slide 1.GIF
Purity:

Above - 95.0%

Technical Data:

We will provide complete documentation support for every Standard Material. All analytical reports such as ¹H NMR, ¹³C NMR, Mass, FT-IR, HPLC Purity/GC Purity/QNMR Purity, Water content by KF/ Loss on Drying/TGA (Thermo-gravimetric Analysis). Certificate of Analysis with potency report. Each Standard Material SER (Structure Elucidation Report) with NMR, Mass, IR spectral interpretation. This whole analytical document can be included in eCTD, ANDA, DMF submissions to regulatory agencies.

Promethazine for peak identification CRS used to verify the performance of the chromatographic system by evaluating parameters like resolution, repeatability, and retention time during system suitability testing before sample analysis.